Protein id	Element symbol	Element name	Scope	Type	Subtype	Class	Subclass	Method	Target length	Reference sequence length	% Coverage of reference	% Identity to reference	Alignment length	Closest reference accession	Closest reference name	HMM accession	HMM description
GCA_002156725.1_00070	emrD	multidrug efflux MFS transporter EmrD	plus	AMR	AMR	EFFLUX	EFFLUX	BLASTP	394	394	100.00	99.24	394	ACN65732.1	multidrug efflux MFS transporter EmrD	NA	NA
GCA_002156725.1_00212	fieF	CDF family cation-efflux transporter FieF	plus	STRESS	METAL	NA	NA	EXACTP	300	300	100.00	100.00	300	BAB89353.1	CDF family cation-efflux transporter FieF	NA	NA
GCA_002156725.1_00767	fosA	FosA5 family fosfomycin resistance glutathione transferase	core	AMR	AMR	FOSFOMYCIN	FOSFOMYCIN	BLASTP	139	139	100.00	98.56	139	WP_004146118.1	FosA5 family fosfomycin resistance glutathione transferase	NF040540.1	FosA5 family fosfomycin resistance glutathione transferase
GCA_002156725.1_01868	kdeA	multidrug efflux MFS transporter KdeA	plus	AMR	AMR	EFFLUX	EFFLUX	BLASTP	410	410	100.00	99.76	410	ABR76310.1	multidrug efflux MFS transporter KdeA	NA	NA
GCA_002156725.1_02396	aadA2	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	core	AMR	AMR	AMINOGLYCOSIDE	STREPTOMYCIN	BLASTP	259	263	98.48	99.61	259	WP_001206356.1	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NF012157.0	ANT(3'')-I family aminoglycoside nucleotidyltransferase
GCA_002156725.1_02397	qacEdelta1	quaternary ammonium compound efflux SMR transporter QacE delta 1	core	STRESS	BIOCIDE	QUATERNARY AMMONIUM	QUATERNARY AMMONIUM	ALLELEP	115	115	100.00	100.00	115	WP_000679427.1	quaternary ammonium compound efflux SMR transporter QacE delta 1	NF000276.2	quaternary ammonium compound efflux SMR transporter QacE
GCA_002156725.1_02398	sul1	sulfonamide-resistant dihydropteroate synthase Sul1	core	AMR	AMR	SULFONAMIDE	SULFONAMIDE	EXACTP	279	279	100.00	100.00	279	WP_000259031.1	sulfonamide-resistant dihydropteroate synthase Sul1	NF000294.1	sulfonamide-resistant dihydropteroate synthase Sul1
GCA_002156725.1_02719	blaSHV-11	broad-spectrum class A beta-lactamase SHV-11	core	AMR	AMR	BETA-LACTAM	BETA-LACTAM	ALLELEP	286	286	100.00	100.00	286	WP_004176269.1	broad-spectrum class A beta-lactamase SHV-11	NF000285.3	SHV family class A beta-lactamase
GCA_002156725.1_03145	asr	acid resistance repetitive basic protein Asr	plus	STRESS	ACID	NA	NA	HMM	116	102	100.00	56.91	123	BAA15331.2	acid resistance repetitive basic protein Asr	NF033636.1	acid resistance repetitive basic protein Asr
GCA_002156725.1_03636	ybtQ	yersiniabactin ABC transporter ATP-binding/permease protein YbtQ	plus	VIRULENCE	VIRULENCE	NA	NA	BLASTP	600	600	100.00	99.50	600	AAC69584.1	yersiniabactin ABC transporter ATP-binding/permease protein YbtQ	NA	NA
GCA_002156725.1_03637	ybtP	yersiniabactin ABC transporter ATP-binding/permease protein YbtP	plus	VIRULENCE	VIRULENCE	NA	NA	BLASTP	570	600	95.00	99.65	570	CAA21388.1	yersiniabactin ABC transporter ATP-binding/permease protein YbtP	NA	NA
GCA_002156725.1_03669	clbN	colibactin non-ribosomal peptide synthetase ClbN	plus	VIRULENCE	VIRULENCE	NA	NA	EXACTP	1455	1455	100.00	100.00	1455	AMH08480.1	colibactin non-ribosomal peptide synthetase ClbN	NA	NA
GCA_002156725.1_03681	clbB	colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbB	plus	VIRULENCE	VIRULENCE	NA	NA	EXACTP	3206	3206	100.00	100.00	3206	AMQ58400.1	colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbB	NA	NA
GCA_002156725.1_04335	oqxA	multidrug efflux RND transporter periplasmic adaptor subunit OqxA	core	AMR	AMR	PHENICOL/QUINOLONE	PHENICOL/QUINOLONE	EXACTP	391	391	100.00	100.00	391	WP_002914189.1	multidrug efflux RND transporter periplasmic adaptor subunit OqxA	NF000272.1	multidrug efflux RND transporter periplasmic adaptor subunit OqxA
GCA_002156725.1_04336	oqxB	multidrug efflux RND transporter permease subunit OqxB	core	AMR	AMR	PHENICOL/QUINOLONE	PHENICOL/QUINOLONE	EXACTP	1050	1050	100.00	100.00	1050	WP_000347934.1	multidrug efflux RND transporter permease subunit OqxB	NF000037.1	multidrug efflux RND transporter permease subunit OqxB
GCA_002156725.1_04672	arsC	glutaredoxin-dependent arsenate reductase	plus	STRESS	METAL	ARSENIC	ARSENATE	HMM	140	141	98.58	78.42	139	AAA21096.1	glutaredoxin-dependent arsenate reductase	NF007456.1	glutaredoxin-dependent arsenate reductase
GCA_002156725.1_05508	hsp20	small heat shock protein sHSP20	plus	STRESS	HEAT	NA	NA	BLASTP	182	189	96.30	99.45	182	CDY80020.1	small heat shock protein sHSP20	NA	NA
GCA_002156725.1_05523	aph(3')-Ia	aminoglycoside O-phosphotransferase APH(3')-Ia	core	AMR	AMR	AMINOGLYCOSIDE	KANAMYCIN	EXACTP	271	271	100.00	100.00	271	WP_000018329.1	aminoglycoside O-phosphotransferase APH(3')-Ia	NF051474.1	aminoglycoside O-phosphotransferase APH(3')-Ia
GCA_002156725.1_05525	mph(A)	Mph(A) family macrolide 2'-phosphotransferase	core	AMR	AMR	MACROLIDE	AZITHROMYCIN/ERYTHROMYCIN/SPIRAMYCIN/TELITHROMYCIN	EXACTP	301	301	100.00	100.00	301	WP_000219391.1	Mph(A) family macrolide 2'-phosphotransferase	NF000254.1	Mph(A) family macrolide 2'-phosphotransferase
GCA_002156725.1_05532	sul1	sulfonamide-resistant dihydropteroate synthase Sul1	core	AMR	AMR	SULFONAMIDE	SULFONAMIDE	EXACTP	279	279	100.00	100.00	279	WP_000259031.1	sulfonamide-resistant dihydropteroate synthase Sul1	NF000294.1	sulfonamide-resistant dihydropteroate synthase Sul1
GCA_002156725.1_05533	qacEdelta1	quaternary ammonium compound efflux SMR transporter QacE delta 1	core	STRESS	BIOCIDE	QUATERNARY AMMONIUM	QUATERNARY AMMONIUM	ALLELEP	115	115	100.00	100.00	115	WP_000679427.1	quaternary ammonium compound efflux SMR transporter QacE delta 1	NF000276.2	quaternary ammonium compound efflux SMR transporter QacE
GCA_002156725.1_05534	aadA2	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	core	AMR	AMR	AMINOGLYCOSIDE	STREPTOMYCIN	BLASTP	259	263	98.48	99.61	259	WP_001206356.1	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA2	NF012157.0	ANT(3'')-I family aminoglycoside nucleotidyltransferase
GCA_002156725.1_05535	dfrA12	trimethoprim-resistant dihydrofolate reductase DfrA12	core	AMR	AMR	TRIMETHOPRIM	TRIMETHOPRIM	EXACTP	165	165	100.00	100.00	165	WP_001083725.1	trimethoprim-resistant dihydrofolate reductase DfrA12	NF000053.2	trimethoprim-resistant dihydrofolate reductase DfrA12
GCA_002156725.1_05542	catA1	type A-1 chloramphenicol O-acetyltransferase	core	AMR	AMR	PHENICOL	CHLORAMPHENICOL	EXACTP	219	219	100.00	100.00	219	WP_000412211.1	type A-1 chloramphenicol O-acetyltransferase	NF000491.1	type A chloramphenicol O-acetyltransferase
GCA_002156725.1_05671	silE	silver-binding protein SilE	plus	STRESS	METAL	SILVER	SILVER	BLASTP	143	143	100.00	91.61	143	AAD11743.1	silver-binding protein SilE	NA	NA
GCA_002156725.1_05672	silS	copper/silver sensor histidine kinase SilS	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	EXACTP	491	491	100.00	100.00	491	SPD96882.1	copper/silver sensor histidine kinase SilS	NA	NA
GCA_002156725.1_05673	silR	copper/silver response regulator transcription factor SilR	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	EXACTP	226	226	100.00	100.00	226	SPD96883.1	copper/silver response regulator transcription factor SilR	NA	NA
GCA_002156725.1_05674	silC	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	EXACTP	461	461	100.00	100.00	461	SPD96884.1	Cu(+)/Ag(+) efflux RND transporter outer membrane channel SilC	NA	NA
GCA_002156725.1_05675	silF	Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone SilF	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	BLASTP	117	117	100.00	99.15	117	KGL71342.1	Cu(+)/Ag(+) efflux RND transporter periplasmic metallochaperone SilF	NA	NA
GCA_002156725.1_05676	silB	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	BLASTP	430	430	100.00	97.67	430	AAD11748.1	Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB	NA	NA
GCA_002156725.1_05677	silA	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	plus	STRESS	METAL	COPPER/SILVER	COPPER/SILVER	BLASTP	1048	1048	100.00	98.85	1048	AAD11749.1	Cu(+)/Ag(+) efflux RND transporter permease subunit SilA	NA	NA
GCA_002156725.1_05679	silP	Ag(+)-translocating P-type ATPase SilP	plus	STRESS	METAL	SILVER	SILVER	BLASTP	815	824	98.79	94.49	816	AAD11750.1	Ag(+)-translocating P-type ATPase SilP	NA	NA
GCA_002156725.1_05683	pcoA	multicopper oxidase PcoA	plus	STRESS	METAL	COPPER	COPPER	EXACTP	605	605	100.00	100.00	605	CAA58525.1	multicopper oxidase PcoA	NA	NA
GCA_002156725.1_05684	pcoB	copper-binding protein PcoB	plus	STRESS	METAL	COPPER	COPPER	BLASTP	298	296	100.00	100.00	296	CAA58526.1	copper-binding protein PcoB	NA	NA
GCA_002156725.1_05685	pcoC	copper resistance system metallochaperone PcoC	plus	STRESS	METAL	COPPER	COPPER	EXACTP	126	126	100.00	100.00	126	CAA58527.1	copper resistance system metallochaperone PcoC	NA	NA
GCA_002156725.1_05686	pcoD	copper resistance inner membrane protein PcoD	plus	STRESS	METAL	COPPER	COPPER	BLASTP	309	309	100.00	99.68	309	CAA58528.1	copper resistance inner membrane protein PcoD	NA	NA
GCA_002156725.1_05687	pcoR	copper response regulator transcription factor PcoR	plus	STRESS	METAL	COPPER	COPPER	EXACTP	226	226	100.00	100.00	226	CAA58529.1	copper response regulator transcription factor PcoR	NA	NA
GCA_002156725.1_05688	pcoS	copper resistance membrane spanning protein PcoS	plus	STRESS	METAL	COPPER	COPPER	BLASTP	466	466	100.00	99.14	466	CAA58530.1	copper resistance membrane spanning protein PcoS	NA	NA
GCA_002156725.1_05689	pcoE	copper resistance system metallochaperone PcoE	plus	STRESS	METAL	COPPER	COPPER	BLASTP	144	144	100.00	94.44	144	CAA58532.1	copper resistance system metallochaperone PcoE	NA	NA
GCA_002156725.1_05700	arsC	glutaredoxin-dependent arsenate reductase	plus	STRESS	METAL	ARSENIC	ARSENATE	EXACTP	141	141	100.00	100.00	141	BAA24824.1	glutaredoxin-dependent arsenate reductase	NF007456.1	glutaredoxin-dependent arsenate reductase
GCA_002156725.1_05701	arsB	arsenite efflux transporter membrane subunit ArsB	plus	STRESS	METAL	ARSENIC	ARSENITE	EXACTP	429	429	100.00	100.00	429	BAA24823.1	arsenite efflux transporter membrane subunit ArsB	NA	NA
GCA_002156725.1_05702	arsA	arsenite efflux transporter ATPase subunit ArsA	plus	STRESS	METAL	ARSENIC	ARSENITE	EXACTP	583	583	100.00	100.00	583	BAA24822.1	arsenite efflux transporter ATPase subunit ArsA	NA	NA
GCA_002156725.1_05703	arsD	arsenite efflux transporter metallochaperone ArsD	plus	STRESS	METAL	ARSENIC	ARSENITE	BLASTP	120	120	100.00	91.67	120	AAB09625.1	arsenite efflux transporter metallochaperone ArsD	NF033727.2	arsenite efflux transporter metallochaperone ArsD
GCA_002156725.1_05704	arsR	As(III)-sensing metalloregulatory transcriptional repressor ArsR	plus	STRESS	METAL	ARSENIC	ARSENIC	EXACTP	116	116	100.00	100.00	116	AET17094.1	As(III)-sensing metalloregulatory transcriptional repressor ArsR	NA	NA
GCA_002156725.1_05721	clpK	heat shock survival AAA family ATPase ClpK	plus	STRESS	HEAT	NA	NA	BLASTP	931	949	97.89	99.25	929	ASF80763.1	heat shock survival AAA family ATPase ClpK	NF033606.1	heat shock survival AAA family ATPase ClpK
GCA_002156725.1_05722	hsp20	small heat shock protein sHSP20	plus	STRESS	HEAT	NA	NA	EXACTP	189	189	100.00	100.00	189	CDY80020.1	small heat shock protein sHSP20	NA	NA
GCA_002156725.1_05739	mph(A)	Mph(A) family macrolide 2'-phosphotransferase	core	AMR	AMR	MACROLIDE	AZITHROMYCIN/ERYTHROMYCIN/SPIRAMYCIN/TELITHROMYCIN	PARTIALP	216	301	63.79	100.00	192	WP_000219391.1	Mph(A) family macrolide 2'-phosphotransferase	NA	NA
GCA_002156725.1_05765	blaSHV-12	extended-spectrum class A beta-lactamase SHV-12	core	AMR	AMR	BETA-LACTAM	CEFIDEROCOL/CEPHALOSPORIN	ALLELEP	286	286	100.00	100.00	286	WP_002904004.1	extended-spectrum class A beta-lactamase SHV-12	NF000285.3	SHV family class A beta-lactamase
GCA_002156725.1_05814	aac(6')-Ib	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	core	AMR	AMR	AMINOGLYCOSIDE	AMIKACIN/KANAMYCIN/TOBRAMYCIN	BLASTP	201	184	100.00	100.00	184	WP_063840280.1	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase	NF033074.0	AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase