GCA_003732505.1|CP018196.1	CCTyper	repeat_region	547874	549231	1358	+	.	ID=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	547874	547903	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT1;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	547904	547940	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER1;Parent=GCA_003732505.1|CP018196.1_1;Note=CTGGATTATAGATTTAACAGGATGATGGATGGAAAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	547941	547970	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT2;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	547971	548004	34	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER2;Parent=GCA_003732505.1|CP018196.1_1;Note=GCAGGAAGAATTCATCATATGATAGTCCATCAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548005	548034	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT3;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548035	548072	38	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER3;Parent=GCA_003732505.1|CP018196.1_1;Note=TTCCTTCGTGTCCGATGTTTGTATTTCGTCTTGAAGTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548073	548102	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT4;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548103	548138	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER4;Parent=GCA_003732505.1|CP018196.1_1;Note=TGATTTTTTGCTTGCAATCTAAAAAAATATTGTATA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548139	548168	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT5;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548169	548205	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER5;Parent=GCA_003732505.1|CP018196.1_1;Note=GTCAAAAGAGAGAATAAGAAAGAAAAGAAGAAGCTAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548206	548235	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT6;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548236	548272	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER6;Parent=GCA_003732505.1|CP018196.1_1;Note=AACTTTGAAACGGTTTTGAGTTCAATTTCTGAAAAAG;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548273	548302	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT7;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548303	548337	35	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER7;Parent=GCA_003732505.1|CP018196.1_1;Note=AATGTAAAAAAAGATTTTTACAAGCACGAGTATAG;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548338	548367	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT8;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548368	548404	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER8;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTTCCCTCCTAGATGTTTCTTTTCATTTTTTCAAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548405	548434	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT9;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548435	548470	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER9;Parent=GCA_003732505.1|CP018196.1_1;Note=TTGCATCTGTCGAGGCGGCTAGAATTATGAAGCGTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548471	548500	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT10;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548501	548535	35	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER10;Parent=GCA_003732505.1|CP018196.1_1;Note=TCACATTCACAGTCGCTTGATTGACTGCTGTGGGC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548536	548565	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT11;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548566	548601	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER11;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTTTTCCCTCTCTTGCAGCCATTCTTTGATTAGAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548602	548631	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT12;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548632	548666	35	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER12;Parent=GCA_003732505.1|CP018196.1_1;Note=TCACATTCACAGTCGCTTGATTGACTGCTGTGGGC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548667	548696	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT13;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548697	548732	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER13;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTTTTCCCTCTCTTGCAGCCATTCTTTGATTAGAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548733	548762	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT14;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548763	548800	38	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER14;Parent=GCA_003732505.1|CP018196.1_1;Note=TCAATTTTTTCTTGATGGTTAGAGCAATACTTATAACC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548801	548830	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT15;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548831	548867	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER15;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTTCCCTCCTAGATGTTTCTTTTCATTTTTTCAAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548868	548897	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT16;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548898	548935	38	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER16;Parent=GCA_003732505.1|CP018196.1_1;Note=AACGTCCAAAGGCTTTCAAGCGTAGGACTTCTAAACAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	548936	548965	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT17;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	548966	549002	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER17;Parent=GCA_003732505.1|CP018196.1_1;Note=GAAGCAAGGAGACATACATAGACAAAGAAAAATATTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	549003	549032	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT18;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	549033	549068	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER18;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTAAACTTCCAAACTTCTCTCCCTCATTTAACAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	549069	549098	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT19;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAAAGTAGAATGTAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	549099	549134	36	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER19;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTAACATCCCAATACTTCTTCCGCCGTCTTGTAGA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	549135	549164	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT20;Parent=GCA_003732505.1|CP018196.1_1;Note=ATTAGAGTATTACTAGAGTAGAATATAAAT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	549165	549201	37	+	.	ID=GCA_003732505.1|CP018196.1_1_SPACER20;Parent=GCA_003732505.1|CP018196.1_1;Note=TTTCTTACTATCTGGAAACATGCTATTTTTTCAACAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	549202	549231	30	+	.	ID=GCA_003732505.1|CP018196.1_1_REPEAT21;Parent=GCA_003732505.1|CP018196.1_1;Note=ATCAGAGTATTTTTAGAATTTATATTAAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	repeat_region	892277	893099	823	+	.	ID=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892277	892306	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT1;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892307	892343	37	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER1;Parent=GCA_003732505.1|CP018196.1_2;Note=CCTTGTAAGATTGGTTTTATACTCATAAGAAAAGCGA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892344	892373	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT2;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892374	892410	37	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER2;Parent=GCA_003732505.1|CP018196.1_2;Note=GCAGACCAAGCAACTGAAAAAATTGGTTTTTTTACAG;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892411	892440	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT3;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892441	892476	36	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER3;Parent=GCA_003732505.1|CP018196.1_2;Note=ATTTCTTCTGATAATTCTTTCATAACATCAATTTTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892477	892506	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT4;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892507	892541	35	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER4;Parent=GCA_003732505.1|CP018196.1_2;Note=GCAACTCCTCTAACATCGCCCCTAATTTCACACGA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892542	892571	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT5;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892572	892606	35	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER5;Parent=GCA_003732505.1|CP018196.1_2;Note=GAAAAATGGCTTATTTGCAATATAGAAGCATATTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892607	892636	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT6;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892637	892673	37	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER6;Parent=GCA_003732505.1|CP018196.1_2;Note=TATGGAATAACAGTGATCCGTTTTTAATTAATGATAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892674	892703	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT7;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892704	892740	37	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER7;Parent=GCA_003732505.1|CP018196.1_2;Note=GCAGACCAAGCAACTGAAAAAATTGGTTTTTTTACAG;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892741	892770	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT8;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892771	892806	36	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER8;Parent=GCA_003732505.1|CP018196.1_2;Note=ATTTCTTCTGATAATTCTTTCATAACATCAATTTTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892807	892836	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT9;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892837	892872	36	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER9;Parent=GCA_003732505.1|CP018196.1_2;Note=AACTCAGGAAATCAACGTCAGGAACTAAACGGAAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892873	892902	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT10;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892903	892937	35	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER10;Parent=GCA_003732505.1|CP018196.1_2;Note=GCAACTCCTCTAACATCGCCCCTAATTTCACACGA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	892938	892967	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT11;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	892968	893002	35	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER11;Parent=GCA_003732505.1|CP018196.1_2;Note=GAAAAATGGCTTATTTGCAATATAGAAGCATATTT;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	893003	893032	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT12;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTTAAC;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	binding_site	893033	893069	37	+	.	ID=GCA_003732505.1|CP018196.1_2_SPACER12;Parent=GCA_003732505.1|CP018196.1_2;Note=TTTTATAGTTTACATAACTATTATCTAAGTCACTAAA;Dbxref=SO:0001459;Ontology_term=CRISPR
GCA_003732505.1|CP018196.1	CCTyper	direct_repeat	893070	893099	30	+	.	ID=GCA_003732505.1|CP018196.1_2_REPEAT13;Parent=GCA_003732505.1|CP018196.1_2;Note=GACTAAATCCAAGTAGATTGGAATTTAATA;Dbxref=SO:0001459;Ontology_term=CRISPR