core_seqid	core_source	core_type	core_start	core_end	core_bax_acc	core_contig_acc	core_bax_acc|contig_acc	core_bax_acc_contig_acc	cenote_input_name	cenote_contig	cenote_phage_region_id	cenote_gene_start	cenote_gene_stop	cenote_gene_name	original_cenote_gene_name	cenote_gene_orient	cenote_contig_length	cenote_dtr_seq	cenote_evidence_accession	cenote_evidence_description	cenote_translation	cenote_Evidence_source	cenote_vscore_category	cenote_chunk_name	cenote_chunk_length	cenote_chunk_start	cenote_chunk_stop	UNI_lookup_ID	pangenome_partition	pangenome_method	pangenome_confidence	pangenome_overlap_length	pangenome_overlap_fraction	pangenome_matching_locus_tag
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	2	277	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	3	278	GCA_019425065_1_117_1	GCA_019425065_1_117_1	+	8564	.	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Lipid transport and metabolism]. 	TNQIGRILERSQCVIAKAPQCFFLRDIYNAHINANKESLEFIDSASMMQYYNNDLFLVEGPAENIKITTPIDFYTFKAYLDVKDSLNVIGL*	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0001	.	unmatched_CDS	none	0	0	.
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	301	1344	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	302	1345	GCA_019425065_1_117_2	GCA_019425065_1_117_2	+	8564	.	PDB:3CPE_A	Large-Terminase	MDTVLIHELERVVCKNVDLYRYFSDKTILVTGATGLIGSMLIKSMLMANRLLSTDIKIIGHVRNINKARQLYWDMHDNDQFTYTSEALSCINESIDYIVHTASPTQSKYFVENPVETLHASIGNTVDCLELGRRKNIIKMLYLSSMEQYGIQLVDNQQMTEVDLGYINHLDVRSSYSEGKRICECYCNAYAEEYGVPVTIARLAQTFGPGIPVEDNRVSMQFAKSVLNCSDIVLHTKGESLSNFCYIMDALTALLVLLKSGESCEAYNICNAKETRSIYEIACLVADEVVNGEISVKFDIPMVNNYGYAPTVKYFLNTDKLENLGWKAEVGMKDAYRLLIEYLKEFH*	hallmark_hmm	common_virus	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0002	persistent	direct	high	1044	1.0	GCA_019425065.1_01213
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	1441	1902	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	1442	1903	GCA_019425065_1_117_3	GCA_019425065_1_117_3	-	8564	.	4OMZ_C	NolR	MDPLRILKALSNPHRLDIILWLKHPEQEFGVQVHANTLIDFPHSVSVKSIQKRCGVSQSSISTFMSILESAELVESRKIDQYTYFRRNEPIIREFGSWYNKEVSIQNDDVEKLLQTVNLEDTSYPIAEESALSSEHPAMELRTKGSRDEDENR*	hhsuite_tools	hypothetical_protein	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0003	persistent	direct	high	461	0.998	GCA_019425065.1_01214
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	2289	3596	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	2290	3597	GCA_019425065_1_117_4	GCA_019425065_1_117_4	+	8564	.	PRK10157	putative oxidoreductase FixC; Provisional	MAIDRNETFDVIVVGAGPAGAAAALRLAEKRVKVLLIERGTAPGAKNMMGGRIYTHSLERIVSDFRDRAPLERKVTKERISIGAGDEMTTVEYSYQDVKPNEESYVVLRAKFDKWLAEEAEKKGALLVTNVQVTELITEGEGKKRRVVGVRCHDDEVYAKLVIIAEGANTVLLEEAGLTGPTAPKTMAVGVKEVYKLKKEDLENRLMLTGDDGMAWLTLGDMTDGLLGGGFIYTNKDSLSVGMVVGIDDIGAASRSVDDMLTAFTSHPRIAPLLKNGQLKEHSAHLVPEGGYRSMPKLGGPGYIIIGDAARMCMNLGYTIRGMDLAIESGICAAEAVNVGLRDENMDRVPKLYEKNIKNSWLHKDLKLYKDMPKFLATHPRIFNEYPKFVNHLMRDVFTVNGDGAVPMMKKLMHRVGDVGLTNLIRDAWKGVRSL*	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0004	persistent	direct	high	1307	0.999	GCA_019425065.1_01215
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	3593	3871	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	3594	3872	GCA_019425065_1_117_5	GCA_019425065_1_117_5	+	8564	.	PRK15449	ferredoxin-like protein FixX; Provisional	MRLEERLGANKYYVDETCPHIQVDGSGFSKEEKMKLVNGCPAGLYTLQENGDLVFDFAGCLECGTCRVLCGDTIVKSWKYPRNSKGIEFRQG*	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0005	persistent	direct	high	278	0.996	GCA_019425065.1_01216
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	3876	4952	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	3877	4953	GCA_019425065_1_117_6	GCA_019425065_1_117_6	+	8564	.	5OW0_B	Electron transfer flavoprotein, beta subunit	MELLVCIKQVPDTSEIRLDPETNNLIRTGLPSIVNPYDMHALEAALSVKDQYEGSRVTVITMGPPQAEAALRECLALGADDAVLVTDRAFGGADTLATSYTIAMAIRHVERNMTRRFQMIFCGKQAIDGDTAQVGPQIAEELGIAQATYACELSVDEGAQKAIVKREHENGYEVIEAPLPLLVTATAELNEPRQPGLWSSIYAKRYEISNLTLRDMPSIDESRIGLAGSPTRVRKVYQPPLRGRVEMINSVEDGAKKVLELAYLIKPEKFAHLLVSVDVPEEPETTDDVDDGIDVKDPVQRAASVESVSPSDFKVVAALHQNREAARAAGAKSNGAVSDSDNSEISTDGSTDVQGGDR*	hhsuite_tools	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0006	persistent	direct	high	1076	0.999	GCA_019425065.1_01217
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	4952	5953	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	4953	5954	GCA_019425065_1_117_7	GCA_019425065_1_117_7	+	8564	.	COG2025	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]. 	MAVTNFDEYRDVFVVADTIDDVVHPVTFELVGQGRRIAKEMGQLVQVMLLGENVQSQAEELVAYGADIVHVFESPLLKYYTTDGYTKVLTDFFEDHKPNILLIGATNNGRDLAPRMSGRMKNGVVADCTILTVDTEEGLVEWTRPALGGNILAEIISPNHRPQMGSVRPNVFKKPERNDASWGRIQYEAFELSPEDIRTKRLEFIPFSKSGYNIQEADIIVAGGRGMGSKENFDKLYELADAIGGVVGATRPLVEKGWIGLPYQVGQTGKTVSPKLYLAFGISGAIQHVSGIAGADTIVAINNDPDAEIFQHANYGIVGDCMEVLHDMLAHLK*	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0007	persistent	direct	high	1001	0.999	GCA_019425065.1_01218
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	6341	7099	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	6342	7100	GCA_019425065_1_117_8	GCA_019425065_1_117_8	+	8564	.	cd05346	classical (c) SDR, subgroup 5. These proteins are members of the classical SDR family, with a canonical active site tetrad and a typical Gly-rich NAD-binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	MSRNVFITGSTSGIGLAIAEAYAKNGDNVLISGRRTELLDTVQSQLMEQYGVRVETLVLDVQNRDDVMSKVPAAIESFGGIDILVNNAGLAQGLDPFQDSDIDDAVTMIDTNVKGLLYVTKAVLPFFIAKNEGHIVNMGSTAGIYAYPGGAVYCATKTAVKTLSDGIRMDTIATDIKVTTIQPGIVETPFSEVRFHGDKEKAAAVYAGIDAVQPQDVADVVVYVTNQPKRMQISDVTIMANQQAAGFMVHKK*	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0008	persistent	direct	high	758	0.999	GCA_019425065.1_01219
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	7211	7846	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	7212	7847	GCA_019425065_1_117_9	GCA_019425065_1_117_9	+	8564	.	.	hypothetical protein	MKSTMKKFLLTAVACACVGTASYCTAGAAGIGSDMSKADAVKADMSQSVEVANEAAAPKTGMPNPMHEFKTVDEAAQYMNIVPQMPKVLPVGYNIESVSTINKDILQVIYTYQDGEDETRNQANGKRITYRVSTLKEDISGEYTQHKVTATEKVDGVKVTFRGGEKMVYLVNWAKDGQNHSMSFERPVTRDMAKAIIANTVAQKQHTKYTK*	.	hypothetical_protein	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0009	persistent	direct	high	635	0.998	GCA_019425065.1_01220
GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote	cenote	CDS	8069	8563	GCA_019425065.1	JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065.1_JAHYYG010000064.1	GCA_019425065.1|JAHYYG010000064.1	GCA_019425065_1_117	GCA_019425065_1_117	8070	8564	GCA_019425065_1_117_10	GCA_019425065_1_117_10	+	8564	.	COG0601	ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism]. 	MYRLVLQRLVSIAGILLAVTLGTFLLMKVSPIDPVAMKFNLVGATPDPVLVEQMREQLGLNDPWWQQYVRWLGQLVRGDFGESILYSLPVATLLGGALPNTLGLVSLSLLMGGVVTIPLGMWSARYQDSWADHVIRLFTFFALAIPGFWVGLLLLYLFGVKLQLV	mmseqs_cdd	nonviral_gene	NaN	.	0	8564	GCA_019425065.1|JAHYYG010000064.1@region_1_8564@tool_cenote_CDS_0010	.	unmatched_CDS	none	0	0	.